Bruise-eze® Cream

Best for:

  • Bruises
  • Haematomas
  • Skin discolouration resulting from: bruises, haematomas, ecchymosis, post-operative bruising
  • Post sclerotherapy haemosiderinic dyschromia (Hyperpigmentation after varicose vein injections)
  • CVI (Chronic Venous Insufficiency) dyschromia (skin discolouration due to pooling of blood in the veins caused by poorly working veins or valves)
  • Prevention of iron-dependent venous ulcers
  • Post non-ablative laser treatment, such as epilation and vascular lasers

 

Ingredients

Purified Water, Lactoferrin LT(Lipid technology), Propanediol, Polyacrylamide & C13-14 Isoparaffin & Laureth-7, Myristyl Myristate, Shea Butter Unsaponifiables, Octyl Palmitate, Simmondsia Chinensis, Dimethyl Sulfone, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Carbomer 980, Disodium Edetate, Sodium Hydroxide, Ethylhexylglycerin, Caprylyl Glycol, Phenoxyethanol.

Bruise-eze® Airless

Easy to use airless pump. Avoids the danger of external contamination

Best for:

  • Bruises
  • Haematomas
  • Skin discolouration resulting from: bruises, haematomas, ecchymosis, post-operative bruising
  • Post sclerotherapy haemosiderinic dyschromia (Hyperpigmentation after varicose vein injections)
  • CVI (Chronic Venous Insufficiency) dyschromia (skin discolouration due to pooling of blood in the veins caused by poorly working veins or valves)
  • Prevention of iron-dependent venous ulcers
  • Post non-ablative laser treatment, such as epilation and vascular lasers

 

Ingredients

Purified Water, Lactoferrin LT(Lipid technology), Propanediol, Polyacrylamide & C13-14 Isoparaffin & Laureth-7, Myristyl Myristate, Shea Butter Unsaponifiables, Octyl Palmitate, Simmondsia Chinensis, Dimethyl Sulfone, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Carbomer 980, Disodium Edetate, Sodium Hydroxide, Ethylhexylglycerin, Caprylyl Glycol, Phenoxyethanol.

Bruise-eze® 2.B

5 x 5mL STERILE single-use applicators

Best for:

  • Haematomas
  • Postoperative ecchymosis
  • Post blepharoplasty
  • Post –sclerotherapy hemosiderinic dyschromias
  • Prevention of iron-dependent venous ulcers
  • Varicose ulcers
  • Pressure sores
  • Fissures, burns
  • Scarring of wounds
  • Post-laser therapy (epilation, ablative & non-ablative)

Indicated for topical therapy of all dermoepidermal tissue’s trophic-dyschromic alterations.

Ingredients

Macrogol 4000, Macrogol 1500, Macrogol 400, Lactoferrin (Lipid Technology), Sorbitol, Glycerol, Allantoin, dl-alpha Tocopheryl acetate

European version:
Kelador® (Brill Pharma, Spain)
Keladerm® (Solinea, Poland)
Kelairon® (Piam, Italy)
Kelapher® (PharmGen, Czech Republic)

Always read the label before purchase. If symptoms worsen or change unexpectedly, talk to your healthcare professional. Follow directions for use.

Healthcare Professionals

Lactoferrin

Lactoferrin (Lf) is an endogenous natural iron-binding chelant. It is found in most body fluids such as saliva, tears, nasal secretions and intestinal fluids, as well as in neutrophils. Lf is synthesised by the mucosal lining and neutrophils, and it is released in response to inflammatory stimuli.

Lf is a multifunctional protein with different activities: anti-inflammatory, antimicrobial, antiviral, antibiofilm and immunomodulatory.

Applications:

Post blepharoplasty

Martínez Grau, G., López, M, Martínez, A., & Gómez, M.C. Use of liposomal lactoferrin in post-blepharoplasty hematoma. Poster session at unknown conference and date.

Dyschromia

Musso, A., Aloesio, R., & Caponi, R. (2015). Use of topical preparation based on lactoferrin in acute and chronic management of skin dyschromias and hypotropisms. Acta Vulnologica, 13(2), 77-89.

Ulcers

Brizzio, E., Castro, M., Narbaitz, M., Borda, N., Carbia, C., Correa, L., Mengarelli, R., Merelli, A., Brizzio, V., Sosa, M., Biancardi, B., & Lazarowski, A. (2012). Vein and Lymphatics, 1:e6.

References:

Siqueiros-Cendón, T., Arévalo-Gallegos, S., Iglesias-Figueroa, B.F., García-Montoya, I.A., Salazar-Martíez, J., & Rascón-Cruz, Q. (2014). Immunomodulatory effects of lactoferrin. Acta Pharmacologica Sinica, 35(5), 557-66. doi: 10.1038/aps.2013.200.

Kell, D.B., Heyden, E.L., & Pretorius, E. (2020). The Biology of lactoferrin, an iron-binding protein that can help defend against viruses and bacteria. Hypothesis and Theory, 11(1221), 1-15. doi: 10.3389/fimmu.2020.01221.

Healthcare Professionals Brochure

1. Martinez Grau, G., Lopez, M., Gomez, MC. (Dept. of Orbital & Ocular Plastics, Brill Pharma, S.L.)Use of Liposomal Lactoferrin in Post-Blepharoplasty Hematoma. In: XXIX SECPOO (Spanish Society of Ocular and Orbital Plastic Surgeons) Congress; 5-7 June 2019; Barcelona.